Insys Therapeutics - PharmaKB

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Company ReportsInsys Therapeutics

Insys Therapeutics(INSY)

Insys Therapeutics was an American specialty pharmaceutical company based in Chandler, Arizona. Its main product was Subsys, a sublingual liquid form of the drug fentanyl. Fentanyl is an extremely fast-acting and powerful opioid used to relieve peaks of pain in cancer patients.

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Trade Name	Drug Name	Approved	Patent Expires	Indication
Dronabinol	Dronabinol	2011-08-19	2028	Vomiting , Nausea , Anorexia

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Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

psychotic disorders

,

pharmacokinetics

,

adolescent behavior

,

psychomotor disorders

,

mental disorders

,

tobacco use disorder

,

magnetic resonance imaging

,

psychological codependency

,

renal insufficiency

,

biological availability

,

dual (psychiatry) diagnosis

,

cigarette smoking

,

headache disorders

,

retinal degeneration

,

retinitis pigmentosa

,

,

,

squamous cell carcinoma of head and neck

,

,

hepatic insufficiency

,

drug interactions

,

,

,

bone marrow diseases

,

knee prosthesis

,

,

therapeutic equivalency

,

,

,

,

,

hiv wasting syndrome

,

drinking behavior

,

developmental disabilities

,

colonic neoplasms

,

,

,

mouth neoplasms

,

skin absorption

,

musculoskeletal diseases

,

,

drug-related side effects and adverse reactions

,

substance-related disorders

,

driving under the influence

,

cognitive dysfunction

,

,

,

bipolar disorder

,

alcoholic intoxication

,

,

thrombocytopenia

,

sickle cell anemia

,

,

breast neoplasms

,

,

chediak-higashi syndrome

,

,

,

,

,

,

parkinson disease

,

attention deficit disorder with hyperactivity

,

metabolic diseases

,

,

,

,

complex regional pain syndromes

,

reflex sympathetic dystrophy

,

major depressive disorder

,

intellectual disability

,

,

behavioral symptoms

,

sleep wake disorders

,

,

,

,

metabolic brain diseases

,

congenital bone marrow failure syndromes

,

,

obsessive-compulsive disorder

,

compulsive personality disorder

,

dystonic disorders

,

,

,

,

chronic pancreatitis

,

renal circulation

,

,

irritable bowel syndrome

,

,

,

brain neoplasms

,

,

,

frontotemporal dementia

,

primary progressive aphasia

,

pick disease of the brain

,

,

neuroinflammatory diseases

,

,

child behavior disorders

,

neurocognitive disorders

,

,

,

,

hidradenitis suppurativa

,

,

essential tremor

,

prostatic neoplasms

,

,

obstructive lung diseases

,

exercise tolerance

,

huntington disease

,

,

juvenile arthritis

,

hematologic diseases

,

vascular dementia

,

neurotoxicity syndromes

,

psoriatic arthritis

,

rheumatoid arthritis

,

,

,

acquired immunodeficiency syndrome

,

autonomic nervous system diseases

,

primary dysautonomias

,

familial dysautonomia

,

,

,

olfaction disorders

,

taste disorders

,

migraine without aura

,

migraine with aura

,

hematopoietic stem cell transplantation

,

graft rejection

,

prader-willi syndrome

,

,

cystic fibrosis

,

systemic lupus erythematosus

,

ulcerative colitis

,

inflammatory bowel diseases

,

,

inborn genetic diseases

,

mucopolysaccharidosis i

,

,

,

niemann-pick diseases

,

type a niemann-pick disease

,

type c niemann-pick disease

,

post-acute covid-19 syndrome

,

,

,

photorefractive keratectomy

,

,

,

,

,

memory disorders

,

caregiver burden

,

traumatic stress disorders acute

,

medical sociology

,

sleep initiation and maintenance disorders

,

neuromyelitis optica

,

hepatocellular carcinoma

,

liver neoplasms

,

,

,

,

,

,

peripheral nervous system diseases

,

,

,

alzheimer disease

,

,

,

marijuana smoking

,

somatoform disorders

,

psychomotor agitation

,

knee osteoarthritis

,

,

,

,

,

problem behavior

,

tourette syndrome

,

,

,

obstructive sleep apnea

,

diabetic neuropathies

,

,

autistic disorder

,

palliative care

,

sleep apnea syndromes

,

wounds and injuries

,

,

anxiety disorders

,

,

diabetes mellitus

,

spinal cord injuries

,

severe combined immunodeficiency

,

kidney diseases

,

traumatic brain injuries

,

opioid-related disorders

,

,

autism spectrum disorder

,

heart disease risk factors

,

,

,

postoperative nausea and vomiting

,

,

bone marrow failure disorders

,

,

,

postherpetic neuralgia

,

,

neoplasm metastasis

,

,

cardiovascular diseases

,

,

drug resistant epilepsy

,

chronic obstructive pulmonary disease

,

,

overactive urinary bladder

,

,

,

fanconi syndrome

,

chronic renal insufficiency

,

type 2 diabetes mellitus

,

wasting syndrome

,

chronic kidney failure

,

trichotillomania

,

systemic scleroderma

,

diffuse scleroderma

,

pervasive child development disorders

,

,

,

,

polyneuropathies

,

peripheral nerve injuries

,

,

,

,

,

,

anorexia nervosa

,

diabetic nephropathies

,

,

excoriation disorder

,

dermatomyositis

,

spinal cord diseases

,

,

,

anterior cruciate ligament injuries

,

,

tibial meniscus injuries

,

marijuana abuse

,

,

,

,

healthy volunteers/patients

,

,

multiple sclerosis

,

,

wiskott-aldrich syndrome

,

muscle spasticity

,

post-traumatic stress disorders

,

traumatic stress disorders

,

alcohol drinking

,

postoperative pain

,

primary immunodeficiency diseases

,

immunologic deficiency syndromes

,

,

migraine disorders

,

myofascial pain syndromes

,

,

,

type 1 hyper-igm immunodeficiency syndrome

,

hyper-igm immunodeficiency syndrome

,

depressive disorder

,

common variable immunodeficiency

,

agammaglobulinemia

,

amyotrophic lateral sclerosis

,

motor neuron disease

,

,

pancreatic neoplasms

,

,

,

head and neck neoplasms

,

,

esophageal diseases

,

replacement arthroplasty knee

,

induced abortion

,

deficiency diseases

,

secondary headache disorders

,

respiratory insufficiency

,

cocaine-related disorders

,

chronic granulomatous disease

,

leukocyte-adhesion deficiency syndrome

,

lymphoproliferative disorders

,

hemophagocytic lymphohistiocytosis

,

personality disorders

,

,

,

,

,

x-linked genetic diseases

,

bipolar and related disorders

,

,

langerhans-cell histiocytosis

,

graft vs host disease

,

adolescent development

,

alcohol-related disorders

,

alcohol abstinence

,

intractable pain

,

,

appetite regulation

,

,

,

,

,

hematologic neoplasms

,

brain concussion

,

gender identity

,

,

gender dysphoria

,

,

sustained virologic response

,

patient readmission

,

shared paranoid disorder

,

aplastic anemia

,

diamond-blackfan anemia

,

shwachman-diamond syndrome

,

dyskeratosis congenita

,

,

sexual behavior

,

risk reduction behavior

,

health behavior

,

atopic dermatitis

,

,

,

blood coagulation disorders

,

hemostatic disorders

,

,

alcohol drinking in college

,

underage drinking

,

,

glucose metabolism disorders

,

,

insulin resistance

,

,

lipid metabolism disorders

,

oxidative stress

,

carbohydrate metabolism

,

electroencephalography

,

cardiac rehabilitation

,

,

,

Lactobacillus acidophilus

diabetes mellitus

,

Antithrombin iii

streptococcal infections

,

rectal neoplasms

,

,

atrial fibrillation

,

mantle-cell lymphoma

,

multiple myeloma

,

plasma cell neoplasms

,

,

central nervous system neoplasms

,

nervous system neoplasms

,

colonic neoplasms

,

streptococcus agalactiae

,

breast neoplasms

,

,

,

ankylosing spondylitis

,

spondylarthritis

,

,

non-small-cell lung carcinoma

,

,

prostatic neoplasms

,

psoriatic arthritis

,

meningococcal infections

,

,

,

bcr-abl positive chronic myelogenous leukemia

,

,

sickle cell anemia

,

,

renal cell carcinoma

,

,

,

vision disorders

,

,

,

meningococcal meningitis

,

,

thrombocytopenia

,

,

neuroendocrine tumors

,

,

myeloid leukemia

,

ovarian neoplasms

,

human influenza

,

myelodysplastic syndromes

,

,

,

gastrointestinal neoplasms

,

digestive system neoplasms

,

b-cell chronic lymphocytic leukemia

,

lymphoid leukemia

,

hepatocellular carcinoma

,

carcinoid tumor

,

malignant carcinoid syndrome

,

serotonin syndrome

,

,

hypercholesterolemia

,

hyperlipoproteinemia type ii

,

homozygous familial hypercholesterolemia

,

chronic obstructive pulmonary disease

,

,

obstructive lung diseases

,

gastrointestinal stromal tumors

,

philadelphia chromosome

,

ovarian epithelial carcinoma

,

axial spondyloarthritis

,

allergic rhinitis

,

,

allergic rhinitis seasonal

,

graft vs host disease

,

pituitary acth hypersecretion

,

acth-secreting pituitary adenoma

,

rheumatoid arthritis

,

,

,

,

,

,

haemophilus influenzae

,

non-hodgkin lymphoma

,

b-cell lymphoma

,

,

hodgkin disease

,

,

,

giant cell arteritis

,

polymyalgia rheumatica

,

follicular lymphoma

,

pancreatic neoplasms

,

,

myeloid leukemia chronic-phase

,

neuroendocrine carcinoma

,

,

,

essential hypertension

,

systolic murmurs

,

multiple sclerosis

,

neoplasm metastasis

,

chronic progressive multiple sclerosis

,

,

small cell lung carcinoma

Aglatimagene besadenovec

lower urinary tract symptoms

,

prostatic hyperplasia

,

,

prostatic neoplasms

,

,

neuroendocrine tumors

,

pituitary neoplasms

,

pituitary acth hypersecretion

,

pituitary diseases

,

acth-secreting pituitary adenoma

,

dumping syndrome

,

,

healthy volunteers/patients

,

,

,

,

neuroendocrine tumors

,

neoplasm metastasis

,

,

b-cell chronic lymphocytic leukemia

,

multiple hamartoma syndrome

,

carcinoid tumor

,

aplastic anemia

,

,

oligodendroglioma

,

,

,

,

cerebellar neoplasms

,

brain neoplasms

,

hepatocellular carcinoma

,

endometrial neoplasms

,

pancreatic neoplasms

,

neuroendocrine carcinoma

,

islet cell carcinoma

,

atopic dermatitis

,

,

,

hodgkin disease

,

,

rheumatoid arthritis

,

,

thrombocytopenic purpura idiopathic

,

thrombocytopenia

,

neurofibromatosis 2

,

neurofibromatosis 1

,

neurofibromatoses

,

,

t-cell lymphoma

,

t-cell lymphoma peripheral

,

t-cell lymphoma cutaneous

,

tuberous sclerosis

,

urinary bladder neoplasms

,

transitional cell carcinoma

,

,

,

myeloproliferative disorders

,

essential thrombocythemia

,

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

non-hodgkin lymphoma

,

mantle-cell lymphoma

,

colorectal neoplasms

,

kidney neoplasms

,

,

,

multiple myeloma

,

plasma cell neoplasms

,

,

,

psoriatic arthritis

,

renal cell carcinoma

,

,

,

,

,

,

,

meningococcal meningitis

,

prostatic neoplasms

,

organ transplantation

,

graft rejection

,

pulmonary arterial hypertension

,

familial primary pulmonary hypertension

,

paroxysmal hemoglobinuria

,

,

chronic urticaria

,

,

hypersensitivity

,

food hypersensitivity

,

peanut hypersensitivity

,

juvenile arthritis

,

,

hereditary autoinflammatory diseases

,

,

familial mediterranean fever

,

,

,

,

,

,

attention deficit disorder with hyperactivity

,

,

,

major depressive disorder

,

depressive disorder

,

,

chronic hepatitis b

,

,

chronic hepatitis

,

heart transplantation

,

bone resorption

,

,

,

myeloid leukemia

,

kidney transplantation

,

breast neoplasms

,

,

bcr-abl positive chronic myelogenous leukemia

,

meningococcal infections

,

,

sickle cell anemia

,

liver transplantation

,

multiple sclerosis

,

chronic obstructive pulmonary disease

,

,

obstructive lung diseases

,

gastrointestinal stromal tumors

,

myeloid leukemia acute

,

human influenza

,

macular degeneration

,

lymphoid leukemia

,

,

,

alzheimer disease

,

choroidal neovascularization

,

pathologic neovascularization

,

,

beta-thalassemia

,

,

parkinson disease

,

relapsing-remitting multiple sclerosis

,

dry eye syndromes

,

type 2 diabetes mellitus

,

diabetes mellitus

,

polycythemia vera

,

primary myelofibrosis

,

graft vs host disease

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

myeloid leukemia chronic-phase

,

,

myelodysplastic syndromes

,

,

,

wet macular degeneration

,

,

,

cystic fibrosis

,

allergic bronchopulmonary aspergillosis

,

pulmonary aspergillosis

,

retinal detachment

,

vascular diseases

,

dissociative disorders

,

polypoidal choroidal vasculopathy

,

diabetic retinopathy

,

pneumococcal infections

,

hemochromatosis

,

,

philadelphia chromosome

,

,

stomach neoplasms

,

,

ankylosing spondylitis

,

spondylarthritis

,

Cintredekin besudotox

,

adrenocortical carcinoma

,

oligodendroglioma

,

,

,

,

,

hyperlipidemias

,

gastrointestinal stromal tumors

,

,

iron-deficiency anemia

,

iron deficiencies

,

,

,

,

small cell lung carcinoma

,

healthy volunteers/patients

,

,

primary myelofibrosis

,

myeloid leukemia acute

,

myeloid leukemia

,

,

hepatocellular carcinoma

,

,

plexiform neurofibroma

,

neurofibromatoses

,

,

,

,

chronic obstructive pulmonary disease

,

,

triple negative breast neoplasms

,

,

,

essential thrombocythemia

,

polycythemia vera

,

,

,

lupus nephritis

,

,

inflammatory breast neoplasms

,

prostatic neoplasms

,

precursor cell lymphoblastic leukemia-lymphoma

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

b-cell chronic lymphocytic leukemia

,

lymphoid leukemia

,

,

wiskott-aldrich syndrome

,

bcr-abl positive chronic myelogenous leukemia

,

,

,

hyperlipoproteinemia type ii

,

organ transplantation

,

homozygous familial hypercholesterolemia

,

cryopyrin-associated periodic syndromes

,

myelodysplastic syndromes

,

,

liver transplantation

,

thrombocytopenic purpura idiopathic

,

thrombocytopenic purpura

,

,

parkinson disease

,

,

,

juvenile arthritis

,

,

,

,

hepatitis b virus

,

,

,

,

vision disorders

,

,

pituitary acth hypersecretion

,

acth-secreting pituitary adenoma

,

,

acute coronary syndrome

,

,

,

pulmonary eosinophilia

,

pancreatic neoplasms

,

,

,

kidney transplantation

,

,

hypercholesterolemia

,

cardiovascular diseases

,

atherosclerosis

,

chronic kidney failure

,

kidney diseases

,

thrombocytopenia

,

,

breast neoplasms

,

,

renal insufficiency

,

,

,

,

chronic renal insufficiency

,

,

renal replacement therapy

,

drug-related side effects and adverse reactions

,

heart transplantation

,

polycystic kidney diseases

,

autosomal dominant polycystic kidney

,

,

,

cystic fibrosis

,

pseudomonas infections

,

type 2 diabetes mellitus

,

diabetes mellitus

,

multiple myeloma

,

plasma cell neoplasms

,

transplantation

,

cytomegalovirus infections

,

communicable diseases

,

,

healthy volunteers/patients

,

hepatic insufficiency

,

esophageal neoplasms

,

,

,

small cell lung carcinoma

,

pancreatic ductal carcinoma

,

multiple myeloma

,

plasma cell neoplasms

,

bronchiolitis obliterans syndrome

,

congenital abnormalities

,

chromosome aberrations

,

brain stem neoplasms

,

chronic hepatitis c

,

chronic hepatitis

,

,

,

medulloblastoma

,

,

,

choroid plexus neoplasms

,

primitive neuroectodermal tumors

,

,

,

neuroepithelial neoplasms

,

ganglioneuroblastoma

,

neuroectodermal tumors

,

phenylketonurias

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

nasopharyngeal carcinoma

,

ureteral neoplasms

,

pelvic neoplasms

,

adenoid cystic carcinoma

,

metabolic syndrome

,

follicular lymphoma

,

,

pancreatic neoplasms

,

kidney neoplasms

,

,

prostatic neoplasms

,

,

,

head and neck neoplasms

,

neurofibromatoses

,

,

liver neoplasms

,

,

,

neurofibromatosis 1

,

plexiform neurofibroma

,

systemic scleroderma

,

diffuse scleroderma

,

b-cell chronic lymphocytic leukemia

,

,

hematologic neoplasms

,

endometrial neoplasms

,

neuroendocrine carcinoma

,

central nervous system neoplasms

,

ovarian neoplasms

,

mantle-cell lymphoma

,

urinary bladder neoplasms

,

squamous cell carcinoma

,

uterine cervical neoplasms

,

myelodysplastic syndromes

,

non-hodgkin lymphoma

,

nervous system neoplasms

,

hypereosinophilic syndrome

,

systemic mastocytosis

,

,

uveal neoplasms

,

squamous cell carcinoma of head and neck

,

t-cell lymphoma

,

transitional cell carcinoma

,

primary myelofibrosis

,

,

graft vs host disease

,

adenocarcinoma of lung

,

diffuse intrinsic pontine glioma

,

disease progression

,

oligodendroglioma

,

neurofibromatosis 2

,

acoustic neuroma

,

,

hodgkin disease

,

islet cell carcinoma

,

hematologic diseases

,

myeloid leukemia accelerated phase

,

,

mast-cell leukemia

,

,

germ cell and embryonal neoplasms

,

,

anaplastic thyroid carcinoma

,

t-cell lymphoma peripheral

,

waldenstrom macroglobulinemia

,

castration-resistant prostatic neoplasms

,

,

cholangiocarcinoma

,

chronic disease

,

large-cell lymphoma anaplastic

,

plasma cell granuloma

,

,

,

,

,

gouty arthritis

,

endocrine gland neoplasms

,

,

urogenital neoplasms

,

male genital diseases

,

prostatic diseases

,

abdominal neoplasms

,

male genital neoplasms

,

genital diseases

,

sjogren's syndrome

,

retinitis pigmentosa

,

,

,

giant cell tumors

,

pigmented villonodular synovitis

,

giant cell tumor of tendon sheath

,

choroidal neovascularization

,

pathologic neovascularization

,

hemangioblastoma

,

von hippel-lindau disease

,

inflammatory breast neoplasms

,

invasive hydatidiform mole

,

multidrug-resistant tuberculosis

,

local neoplasm recurrence

,

t-cell lymphoma cutaneous

,

peutz-jeghers syndrome

,

acute coronary syndrome

,

st elevation myocardial infarction

,

malignant mesothelioma

,

,

type 1 diabetes mellitus

,

,

intestinal neoplasms

,

testicular neoplasms

,

,

brain stem infarctions

,

,

sturge-weber syndrome

,

klippel-trenaunay-weber syndrome

,

neurofibrosarcoma

,

nerve sheath neoplasms

,

carcinoma in situ

,

breast diseases

,

multiple hamartoma syndrome

,

,

urologic neoplasms

,

fallopian tube neoplasms

,

t-cell leukemia

,

localized scleroderma

,

myelomonocytic leukemia chronic

,

myelomonocytic leukemia acute

,

myelomonocytic leukemia juvenile

,

,

,

ovarian epithelial carcinoma

,

sickle cell anemia

,

streptococcus agalactiae

,

colorectal neoplasms

,

myeloid leukemia acute

,

,

,

neoplasm metastasis

,

brain neoplasms

,

hepatocellular carcinoma

,

,

thyroid neoplasms

,

thyroid diseases

,

chronic urticaria

,

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

,

triple negative breast neoplasms

,

,

colonic neoplasms

,

,

carcinoid tumor

,

pulmonary arterial hypertension

,

familial primary pulmonary hypertension

,

,

gastrointestinal neoplasms

,

stomach neoplasms

,

rectal neoplasms

,

,

meningococcal meningitis

,

meningococcal infections

,

rheumatoid arthritis

,

organ transplantation

,

graft rejection

,

digestive system neoplasms

,

cutaneous malignant melanoma

,

,

lymphangioleiomyomatosis

,

lupus nephritis

,

,

hypersensitivity

,

peanut hypersensitivity

,

multiple sclerosis

,

relapsing-remitting multiple sclerosis

,

interstitial lung diseases

,

,

lung transplantation

,

malignant carcinoid syndrome

,

serotonin syndrome

,

food hypersensitivity

,

psoriatic arthritis

,

,

muscular atrophy

,

spinal muscular atrophy

,

,

,

,

idiopathic pulmonary fibrosis

,

pulmonary fibrosis

,

,

chronic inducible urticaria

,

infectious skin diseases

,

bacterial skin diseases

,

,

,

myeloid leukemia

,

,

bcr-abl positive chronic myelogenous leukemia

,

breast neoplasms

,

,

,

non-small-cell lung carcinoma

,

renal cell carcinoma

,

,

kidney transplantation

,

philadelphia chromosome

,

lymphoid leukemia

,

neuroendocrine tumors

,

gastrointestinal stromal tumors

,

precursor cell lymphoblastic leukemia-lymphoma

,

,

myeloid leukemia chronic-phase

,

liver transplantation

,

renal insufficiency

,

tuberous sclerosis

,

chronic kidney failure

,

heart transplantation

,

kidney diseases

,

islet cell adenoma

,

,

,

macular degeneration

,

,

,

,

autosomal dominant polycystic kidney

,

communicable diseases

,

polycystic kidney diseases

,

,

diabetes mellitus

,

tick-borne encephalitis

,

,

immunosuppression therapy

,

cytomegalovirus infections

,

,

large cell carcinoma

,

vascular diseases

,

,

,

vision disorders

,

,

type 2 diabetes mellitus

,

cross-sectional studies

,

,

polyomavirus infections

,

cryopyrin-associated periodic syndromes

,

polycythemia vera

,

,

,

systolic heart failure

,

myocardial infarction

,

,

,

inferior wall myocardial infarction

Microcrystalline cellulose

,

small cell lung carcinoma

,

,

falciparum malaria

,

,

hepatic insufficiency

,

myelodysplastic syndromes

,

,

,

lymphoid leukemia

,

b-cell chronic lymphocytic leukemia

,

dermatomyositis

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

non-hodgkin lymphoma

,

,

,

,

,

,

,

cerebral hemorrhage

,

hemorrhagic stroke

,

essential thrombocythemia

,

polycythemia vera

,

primary myelofibrosis

,

,

,

lupus nephritis

,

,

peritoneal neoplasms

,

intestinal obstruction

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

t-cell leukemia

,

b-cell leukemia

,

basal cell carcinoma

,

,

basal cell nevus syndrome

,

basal cell neoplasms

,

,

,

graft vs host disease

,

bronchiolitis obliterans syndrome

,

multiple myeloma

,

plasma cell neoplasms

,

alzheimer disease

,

cognitive dysfunction

,

,

renal insufficiency

,

chronic renal insufficiency

,

kidney diseases

,

,

hyperphosphatemia

,

myeloid leukemia acute

,

myeloid leukemia

,

chronic inflammatory demyelinating polyradiculoneuropathy

,

polyradiculoneuropathy

,

human influenza

,

renal cell carcinoma

,

hepatocellular carcinoma

,

,

liver neoplasms

,

gastrointestinal stromal tumors

,

,

multiple sclerosis

,

,

relapsing-remitting multiple sclerosis

,

kidney transplantation

,

type 2 diabetes mellitus

,

chronic progressive multiple sclerosis

,

diabetes mellitus

,

neoplasm metastasis

,

healthy volunteers/patients

,

,

retinal vein occlusion

,

nerve degeneration

,

,

,

depressive disorder

,

neurobehavioral manifestations

,

,

pituitary acth hypersecretion

,

acth-secreting pituitary adenoma

,

,

,

,

cataract extraction

,

capsule opacification

,

,

disease progression

,

hodgkin disease

,

,

pancreatic neoplasms

,

pancreatic ductal carcinoma

,

,

colonic neoplasms

,

rectal neoplasms

,

carotid artery diseases

,

atherosclerosis

,

,

hematologic neoplasms

,

sezary syndrome

,

b-cell chronic lymphocytic leukemia

,

prolymphocytic leukemia t-cell

,

t-cell lymphoma

,

prolymphocytic leukemia

,

t-cell lymphoma peripheral

,

t-cell lymphoma cutaneous

,

prolymphocytic leukemia b-cell

,

renal cell carcinoma

,

kidney neoplasms

,

gastrointestinal neoplasms

,

biliary tract neoplasms

,

hypercholesterolemia

,

,

,

hyperlipidemias

,

,

colorectal neoplasms

,

hyperlipoproteinemias

,

postmenopausal osteoporosis

,

hyperlipoproteinemia type v

,

familial combined hyperlipidemia

,

stomach neoplasms

,

non-small-cell lung carcinoma

,

,

,

esophageal neoplasms

,

type 2 diabetes mellitus

,

diabetes mellitus

,

vitamin d deficiency

,

non-hodgkin lymphoma

,

,

esophageal squamous cell carcinoma

,

hyperlipoproteinemia type ii

,

,

,

,

cardiovascular diseases

,

coronary disease

,

coronary artery disease

,

myocardial ischemia

,

,

peripheral arterial disease

,

peripheral vascular diseases

,

heart transplantation

,

polycystic ovary syndrome

,

,

,

atopic dermatitis

,

,

substance-related disorders

,

,

chronic hepatitis c

,

intravenous substance abuse

,

,

chronic hepatitis

1

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